Pastor Quentin Dillard took over Greater Faith Temple of Praise after his father had a stroke. Quentin never wanted to be a pastor but soon discovers he has been called to lead this Pentecostal church with more than one thousand members. He immediately faces conflict from his father-the classic old school versus new school argument-on how the church should be run, but this conflict is the least of Quentin's worries. The Coronavirus is in its embryonic stages in the United States, forcing Quentin to make a choice. Should he continue to have live services, even though people are beginning to get sick, or should he close the church and face the spiritual consequences of that action? Quentin's decision to keep the church open is not solely based on his spiritual beliefs, though. A large loan from a malicious lender has placed intense pressure on the church staying open. Holy Pandemic traces Quentin's struggles with his denomination, threats from his lender, escalating sickness in the church, and constant battles with his father. He relies on his faith to keep going but knows his faith is weakening as the virus and internal and external pressures mount. As the church's financial struggles grow, Quentin faces the moral and spiritual dilemma of whether to continue preaching while a pandemic ravages the world.